As long as alignment is good and correct tire pressure is maintained you shouldn't have an issue. Having individual wheel weights rather than axle weights helps in the inflation area.
One thing to do is to crawl around the coach and record the DOT dates off the tires. I have seen new motorhomes come off the dealer's lot with tires that were up to 2 years old. In some cases I've seen a one year difference between tires on the same axle and even between inner and outer duals.
In the last 7 years I bought 2 sets of tires due to age. They were expensive but in both cases the price included a free motorhome.