And the answer is, I gave up and took it to a car audio shop. 20 minutes later the radio was removed, fuse replaced, and reinstalled. Cost me $25 even and I watched the process. I could now do it myself but would take a little longer than the 20 minutes the tech took, but not much.
The deal is on a modern (2015) E350/450 Super Duty Chassis the entire dash fascia from the left of the steering wheel to the glove box must be removed. It's all one piece. I was surprised to find it simply snaps off the dash panel all the plug in switches disconnected and then the radio is held in by 4 bolts. The panel surrounding the radio is not removable, it is the actual mount. Thanks to all who guessed and gave me ideas on how to remove it.
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