I'm not sure which tankless water heater you have - we have a Girard. You can use compressed air to blow the lines out. That works very well.
But if you want to use anti freeze, you do not require a bypass for the heater. In fact, it probably better to send the anti freeze through the lines to ensure there's no water left anywhere. (The reason for a bypass is to save filling up the tank with 6 gallons of anti freeze.)
Make sure you turn the water heater off - at the water heater itself. There's a switch on the heater. Some heaters will turn on at a pre determined temperature. If you boil off the anti freeze, the lines would be empty. And running the heater with empty lines is not a good thing.
__________________
|