Hi Rick, I have only been RVing for a couple of years, but have a good amount of automotive experience which helps quite a bit with our motorhome. With that kind of mileage I would check the underside for extensive rust on critical components like the exhaust system, leaf springs, steering components and fender/compartment supports and braces. I found that problem on my 1999 Holiday Rambler. Also, have someone or yourself check the roof and sidewalls (inside and out) for leaks, open seems etc. Beyond that I would have a knowledgeable mechanic inspect the drivetrain. Also, make sure all of the motorhome facilities are in working order.