Lots of good advice listed previously. And, given your trailer hauling experience, you likely already know and do this. My 2 cents worth is, on Interstates and other multi-lane highways, don't try to keep up with the usual flow of traffic. I stay mostly in the right-hand lane and set speed control around 63 mph. Every RV I've ever driven, over the past 40+ years handles better at that speed, rather than the 70 to 80 mph most cars run on Interstates. Let them blow by you and be prepared for the side winds when the big rigs pass you. You'll also get better mpg, staying under 65. You'll do fine. Safe travels!