I ran nitrogen in my second set of 16 ply tires on my F550 crew cab pickup
70k on the first set and gave the truck to little brother with second set still on the ground
No measurable difference than with the air in the first set monitoring temperature with similar loads
Both sets were inflated to 115 psig steering and duals
If nitrogen is free I use it, otherwise shop air compressor
A few tire shops include nitrogen an option
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