Without knowing what brand your tankless water heater is; here's something I found on the web for a Girard tankless water heater.
Water heater come on and then locks out with an E-1 code.
Confirm that gas tank is turned on and that they have propane in the tanks.
If this is the first start up, or a refilled tank, consider that the customer needs to try multiple times for startup. Turn the
burners on the range to get the gas moving through the system.
Tap on the gas valve. If it starts, then replace the gas valve.
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Smell for gas coming out of the exhaust.
If the weather is cold, do they have enough propane in the tank?
Is the regulator on the tank working?
Replace gas valve.
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