I have a new 2021 Axis 24.1 built on the Ford E350 chassis with the new V8. Weight and how you drive does make a difference in fuel milage. I have driven 4,000 miles this year, about 1/3 interstate and 2/3 secondary and hilly roads here in the NE. The lowest I got was 11.3 mpg (hilly secondary roads) and the highest was 12.8 (on the interstate at 60-65 mpg). I average 12.0.
David
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