I'm 67, and the wife is close behind. Our cover weighs maybe 35# ??? The key is having it rolled properly when stored.
I walk up the ladder with the front end in hand. Once on the roof, I drag the rest up... then pull it forward to the cab-over. You don't need to lug the ENTIRE cover up the ladder! There I toss the front part over, where the wife grabs the straps and we center it side to side. She secures it under the front bumper. Then I gradually work backwards, unrolling, centering as the wife finds the side straps. I fit the cover over the "solar panel hole" and keep working backward. When I get to the ladder, I walk down the ladder, pulling the back section down.
All that's left is securing the "belly straps" under the motorhome which keeps the cover cinched tight.
I guess if you're not in decent physical shape, or poor health this could be a challenge. Fear of heights could also affect some. But honestly, for me - it's an easier task than a total wax job on the entire motorhome!! Know your limits, work safe AND smart!