I looked into this a while back when renting a Class C built on Ford E-Series, because it came with a spare tire but no jack or lug wrench. I wanted to be prepared just in case.
It turned out the jack from my E-350 SRW van is rated at only 2.0 tons, while the DRW E-Series (whether E-350 or E-450) were rated at 4.0 tons according to Ford specs.
While the spare-tire winch from a regular van works, I would not use its jack because it's not strong enough.
Regarding lug wrench, I can't recall 100% but think mine didn't work on rear tires because of added DRW dish. The handle would hit the tire. Fortunately I have other tools that could substitute.
I'd just make sure the jack and wrench come from Dual Rear Wheel E-Series, and that they are in good shape.
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