This article may help shed some light on just how complicated and expensive these decisions are for Ford and other manufacturers.
Ford Canada labor deal investment mainly for engines-sources | Reuters
Regarding 6.2L V8 power, in Super Duty pickup trucks its rating is higher than the V10's. Maximum torque is a little higher too compared to 2-valve V10, although it comes in a little later in RPM range so at +/- 2,000 RPM cruise range it may be a little lower.
Ford may rate the V8 differently when installed in E-Series. That's a major piece of the puzzle still missing.
By the way, the Reuters report mentions a new large V8 for Super Duty applications. If report is accurate, that may be the engine that replaces all V10s. The present V10s seem to have too many emissions and noise issues to keep long term.