Condolences. We travel with two standard size Poodles in a 22' Motor home.
The key to keeping your sanity is to get the dogs to stay in their space and stay out from under foot when overnighting. I made a board to fit across the driver seats and the beds go on top of it for sleeping. When under way, one will sit between the driver passenger seat and look out the window for hours. The other sits up on the dinette and looks out the window. I made slip covers for all the cushions on the dinette. Works out ok. Your biggest nightmare will be when you are inside during heavy downpours. They got to go and you need to wipe off feet when you are finished walking them.