A lot depends on what you are doing and where you drive. If you tow anything you are better off with 4.30 or 4.56. Even your MPG may be better. Sure higher RPM's but the motor is also not working as hard so its a trade off. If you do lots of mountians or tow a lot 4.30 and I would go 4.56. I think on my 2016 e450 chassis I have 4.56 but may be 4.30. I tow a 7,000lb boat and it has no problems pulling it anywhere.
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