2020 Thor Quantum 32 ft class C
My wife and I are planning a trip from Camino,CA to the Great Smoky Mountains and Blue Ridge Pkwy. Is 2 weeks long enough and any suggestions how you would incorporate the two. Trip planned for Sept 16 to Oct 20 2025.
We do this trip (more or less) almost every year, as we have kids living in Charlotte. Our departure point is Salt Lake City, and we take at least 5 days each way. According to Google maps, from Camino you are looking at 2620 miles one way (taking I-40). Assuming you take 7 days to travel that, you'll need to average 350 miles a day.
To actually enjoy your time once you are there, I'd suggest two weeks driving the parkways, and seeing the park. While you're there Gatlinburg/Pigeon Forge are worth a look, as well as Dollywood if you are an amusement park type. The Biltmore Estate is also pretty close, assuming it's open (it was damaged in the recent floods in Asheville).
Doing the math, 3-4 weeks is probably a more realistic time estimate.
Going in September I'd suggest staying south on I-40 or the parallel backroads. There are some really nice sights to see along that route, as well as some pretty cool mom and pop RV parks.
A final suggestion - try and stay in an Army Corps of Engineers camopground every time you have the opportunity. They are uniformly beautiful, usually very low density, all have amazing water features, and are really cheap.
Safe travels!