Check out this website:
http://thelonglongroad.com/
and her prior website:
http://48in366.com/
She is pretty much full timing it in an Axis with only her and a puppy. No car, no rentals.
Unhooking up and re-hooking up really isn't an issue. Especially if you only use water and electric (just hookup sewer when you need to dump). Leave a cone or sign at your site just in case and off you go.