When we did that trip in our Axis: I parked it in front of our house the night before and turned on the furnace. In the morning I de-winterized, sanitized, etc. then we left.
For our trip home I did the opposite: Once we got home and unloaded the camper I winterized and then turned off the furnace.
All of the 24.1's plumbing is inside the coach on the floor--none of it is under the floor. In addition, the long run that goes to the back, around the beds, and into the bathroom is accompanied by a furnace vent (to warm the bathroom) which keeps that plumbing warm as well.
The waste/drains all go under the floor to the tanks but those pipes are empty unless the waste tanks are full!